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Immune Hematology. Diagnosis and Management of Autoimmune Cytopenias

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This text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children. The book is divided into four sections, each of which focuses on a major autoimmune cytopenia. The first section features background, pathophysiology, presentation, evaluation, and treatment strategies for immune thrombocytopenia (ITP), the most common cause of antibody-mediated platelet destruction. The second section reviews common forms and treatment strategies for autoimmune hemolytic anemia (AIHA), including a chapter dedicated specifically to Evans Syndrome. The third section comprehensively reviews the pathophysiology, diagnosis and current management approaches to thrombotic thrombocytopenic purpura (TTP), a potentially life-threatening autoimmune syndrome. The book concludes with a final section on autoimmune neutropenia. Each section includes a review of common underlying systemic autoimmune conditions and immune deficiency syndromes that can accompany or cause autoimmune cytopenias.

Part I Immune Thrombocytopenia (ITP)
1 Background of Immune Thrombocytopenia
2 Pathophysiology of Immune Thrombocytopenia
3 Presentation and Evaluation of Immune Thrombocytopenia
4 The Treatment of Immune Thrombocytopenia

Part II Autoimmune Hemolytic Anemia (AIHA)
5 Background, Presentation and Pathophysiology of Autoimmune Hemolytic Anemia
6 Treatment of Autoimmune Hemolytic Anemia
7 Evans Syndrome: Background, Clinical Presentation, Pathophysiology, and Management

Part III Thrombotic Thrombocytopenic Purpura (TTP)
8 Background and Presentation of Thrombotic Thrombocytopenic Purpura
9 Pathophysiology of Thrombotic Thrombocytopenic Purpura

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