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Neonatology – Gomella – 7 Edition

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Neonatology - Gomella - 7 Edition

Neonatology – Gomella – 7 Edition

Neonatology – Gomella – 7 Edition PDF

I am pleased to present the seventh edition of Neonatology, the 25th anniversary silver edition. The first edition was published in 1988 and was started during my neonatology fellowship at University of Kentucky Medical Center in Lexington. The origins of the manual were fairly simple and started as a series of handouts designed to help students and residents get through their NICU rotation. Because of a complicated twin pregnancy during my fellowship, I had to delay my training and finish my required neonatology fellowship at Johns Hopkins University. Therefore, the roots of this manual began at University of Kentucky while I was a fellow with Dr. Doug Cunningham’s program, but it was ultimately completed while I was finishing my fellowship at Johns Hopkins University and working at the Bayview campus under Dr. Fabien Eyal. This has made the book somewhat unique since it was originally written from the perspective of two programs. Over the years this fact, along with the addition of other authors from around the United States and the world, helps to diversify our contributors and provide a more varied overview of the field.

In this seventh edition we reformatted the table of contents to make it more user friendly and hopefully more logical. Section I includes “Fetal Assessment,” “Obstetric Anesthesia and the Neonate,” “Resuscitation of the Newborn,” and “Infant Transport.” Section II encompasses basic assessment and management of a newborn. Section III includes advanced management such as the evolving areas of complementary and alternative medical therapies and bioethics in neonatology. Section IV includes all the basic and advanced procedures commonly used in neonatology, and new chapters include “Transillumination,” “Therapeutic Hypothermia,” “Laryngeal Mask Airway,” “Peripheral IV Extravasation and Infiltration: Initial Management,” and “Transpyloric Intubation” was added to the “Gastric Intubation” chapter. One of the most popular sections of the book, the On-Call Problems section, now includes a total of 34 common neonatal problems. “Hematuria” was added as a new on-call problem. Section VI, Diseases and Disorders, covers all the common and a few not so common, but clinically important, diseases of the neonate. We have added new chapters on coagulation disorders, transient neonatal myasthenia gravis, pertussis, and tuberculosis. The section on neonatal pharmacology includes significant updates of medications for neonates. We believe it to be the most comprehensive list of medications found in a manual such as ours. The “Effects of Drugs and Substances on Lactation and Infants” chapter has been revised to include the most common medications that might be used by a breast-feeding mother. The appendices include other useful reference tables and information. A hallmark of our book has been noting areas that are controversial, and this edition continues that tradition.

In addition to completely updating each chapter we have added several new clinically important areas such as pain management in the neonate. Several years ago, the concept of neonatal pain was occasionally mentioned, but definitive treatment plans did not exist. Since the American Academy of Pediatrics (AAP) has produced pain management guidelines for certain procedures, we have also added pain management in each procedure where appropriate. This addition provides AAP recommendations and also covers some recommendations from other countries. We have also added a chapter on “Pain in the Neonate” in Section III. The chapter “Sedation and Analgesia” goes over pain and sedation issues when on call. Also new to this edition are 21 color plates of common and not so common pictures of neonatal rashes and disorders. This corresponds to our chapter, “Rash and Dermatologic Problems.”

Another exciting ongoing aspect of this manual is its global reach. As we have a growing number of readers all over the world, we have added an international editorial board of physicians. They are from Poland, the Netherlands, the Philippines, Finland, Japan, India, Canada, and Australia. These physicians, along with our many international contributors, help to make the manual a useful reference worldwide. The manual has been translated into 12 different languages over the last 25 years. These translations include Russian, Spanish, Portuguese, Polish, Chinese (short and long form), Turkish, Greek, Yugoslavian (now Serbian), Italian, Hungarian, and Korean.

Section I: Antepartum, Intrapartum, Delivery, and Transport Management
1: Fetal Assessment
2: Obstetric Anesthesia and the Neonate
3: Resuscitation of the Newborn
4: Infant Transport

Section II: Basic Management
5: Gestational Age and Birthweight Classification
6: Newborn Physical Examination
7: Temperature Regulation
8: Respiratory Management
9: Fluid and Electrolytes
10: Nutritional Management

Section III: Advanced Management
11: Imaging Studies
12: Management of the Extremely Low Birthweight Infant During the First Week of Life
13: Management of the Late Preterm Infant
14: Pain in the Neonate
15: Newborn Screening
16: Studies for Neurologic Evaluation
17: Blood Component Therapy
18: Extracorporeal Life Support in the Neonate
19: Follow-Up of High-Risk Infants
20: Complementary and Alternative Medical Therapies in Neonatology
21: Neonatal Bioethics

Section IV: Procedures
Principles of Neonatal Procedures
22: Arterial Access: Arterial Puncture (Radial Artery Puncture)
23: Arterial Access: Percutaneous Arterial Catheterization (Radial Arterial Line)
24: Arterial Access: Umbilical Artery Catheterization
25: Bladder Aspiration (Suprapubic Urine Collection)
26: Bladder Catheterization
27: Chest Tube Placement
28: Defibrillation and Cardioversion
29: Endotracheal Intubation and Extubation
30: Exchange Transfusion
31: Peripheral IV Extravasation and Infiltration: Initial Management
32: Gastric and Transpyloric Intubation
33: Heelstick (Capillary Blood Sampling)
34: Laryngeal Mask Airway
35: Lumbar Puncture (Spinal Tap)
36: Ostomy Care
37: Paracentesis (Abdominal)
38: Pericardiocentesis
39: Therapeutic Hypothermia
40: Transillumination
41: Venous Access: Intraosseous Infusion
42: Venous Access: Percutaneous Central Venous Catheterization
43: Venous Access: Peripheral Intravenous Catheterization
44: Venous Access: Umbilical Vein Catheterization
45: Venous Access: Venipuncture (Phlebotomy)

Section V: On-Call Problems
46: Abnormal Blood Gas
47: Apnea and Bradycardia (“A’s and B’s”)
48: Arrhythmia
49: Bloody Stool
50: Counseling Parents Before High-Risk Delivery
51: Cyanosis
52: Death of an Infant
53: Eye Discharge and Conjunctivitis
54: Gastric Aspirate (Residuals)
55: Gastrointestinal Bleeding from the Upper Tract
56: Hematuria
57: Hyperbilirubinemia, Conjugated
58: Hyperbilirubinemia, Unconjugated
59: Hyperglycemia
60: Hyperkalemia
61: Hypertension
62: Hypoglycemia
63: Hypokalemia
64: Hyponatremia
65: Hypotension and Shock
66: Is the Infant Ready for Discharge?
67: No Stool in 48 Hours
68: No Urine Output in 24 Hours
69: Pneumoperitoneum
70: Pneumothorax
71: Polycythemia
72: Poor Perfusion
73: Postdelivery Antibiotics
74: Pulmonary Hemorrhage
75: Rash and Dermatologic Problems
76: Sedation and Analgesia
77: Seizure Activity
78: Traumatic Delivery
79: Vasospasms and Thromboembolism

Section VI: Diseases and Disorders
80: ABO Incompatibility
81: Air Leak Syndromes
82: Anemia
83: Apnea
84: Bronchopulmonary Dysplasia/Chronic Lung Disease
85: Calcium Disorders (Hypocalcemia, Hypercalcemia)
86: Chlamydial Infection
87: Coagulation Disorders
88: Common Multiple Congenital Anomaly Syndromes
89: Congenital Heart Disease
90: Cytomegalovirus
91: Disorders of Sex Development
92: Enteroviruses and Parechoviruses
93: Eye Disorders of the Newborn
94: Gonorrhea
95: Hepatitis
96: Herpes Simplex Viruses
97: Human Immunodeficiency Virus
98: Hydrocephalus and Ventriculomegaly
99: Hyperbilirubinemia, Direct (Conjugated Hyperbilirubinemia)
100: Hyperbilirubinemia, Indirect (Unconjugated Hyperbilirubinemia)
101: Inborn Errors of Metabolism with Acute Neonatal Onset
102: Infant of a Diabetic Mother
103: Infant of Substance-Abusing Mother
104: Intracranial Hemorrhage
105: Intrauterine Growth Restriction (Small for Gestational Age)
106: Lyme Disease
107: Magnesium Disorders (Hypomagnesemia, Hypermagnesemia)
108: Meconium Aspiration
109: Meningitis
110: Methicillin-Resistant Staphylococcus aureus Infections
111: Multiple Gestation
112: Myasthenia Gravis (Transient Neonatal)
113: Necrotizing Enterocolitis
114: Neural Tube Defects
115: Orthopedic and Musculoskeletal Problems
116: Osteopenia of Prematurity
117: Parvovirus B19 Infection
118: Patent Ductus Arteriosus
119: Perinatal Asphyxia
120: Persistent Pulmonary Hypertension of the Newborn
121: Pertussis
122: Polycythemia and Hyperviscosity
123: Renal Failure, Acute (Acute Kidney Injury)
124: Respiratory Distress Syndrome
125: Respiratory Syncytial Virus
126: Retinopathy of Prematurity
127: Rh Incompatibility
128: Rubella
129: Seizures
130: Sepsis
131: Spontaneous Intestinal Perforation
132: Surgical Diseases of the Newborn: Abdominal Masses
133: Surgical Diseases of the Newborn: Abdominal Wall Defects
134: Surgical Diseases of the Newborn: Alimentary Tract Obstruction
135: Surgical Diseases of the Newborn: Diseases of the Airway, Tracheobronchial Tree, and Lungs
136: Surgical Diseases of the Newborn: Retroperitoneal Tumors
137: Surgical Diseases of the Newborn: Urologic Disorders
138: Syphilis
139: Thrombocytopenia and Platelet Dysfunction
140: Thyroid Disorders
141: TORCH Infections
142: Toxoplasmosis
143: Transient Tachypnea of the Newborn
144: Tuberculosis
145: Ureaplasma Infection
146: Urinary Tract Infection
147: Varicella-Zoster Infections

Section VII: Neonatal Pharmacology
148: Medications Used in the Neonatal Intensive Care Unit
149: Effects of Drugs and Substances on Lactation and Infants

Appendix A: Abbreviations Used in Neonatology
Appendix B: Apgar Scoring
Appendix C: Blood Pressure Determinations
Appendix D: Chartwork
Appendix E: Immunization Tables
Appendix F: Isolation Guidelines
Appendix G: Temperature Conversion Table
Appendix H: Weight Conversion Tablea




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