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Principles of Tissue Engineering – 5th Edition PDF

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Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system.

As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future.

This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.

INTRODUCTION TO TISSUE ENGINEERING
1. From Mathematical Models to Clinical Reality
2. Stem Cells as Building Blocks
3. Moving into the Clinic
4. Tissue Engineering: Current Status and Future Perspectives
PART ONE: THE BASIS OF GROWTH AND DIFFERENTIATION
5. Molecular Biology of the Cell
6. Molecular Organization of Cells
7. The Dynamics of Cell-ECM Interactions, with Implications for Tissue Engineering
8. Matrix Molecules and Their Ligands
9. Morphogenesis and Tissue Engineering
10. Gene Expression, Cell Determination, Differentiation, and Regeneration
PART TWO: IN VITRO CONTROL OF TISSUE DEVELOPMENT
11. Engineering Functional Tissues: In Vitro Culture Parameters
12. Principles of Bioreactor Design for Tissue Engineering
13. Regulation of Cell Behavior by Extracellular Proteins
14. Cell and Matrix Dynamics in Branching Morphogenesis
15. Mechanobiology, Tissue Development and Organ Engineering
PART THREE: IN VIVO SYNTHESIS OF TISSUES AND ORGANS
16. In Vivo Synthesis of Tissues and Organs
PART FOUR: BIOMATERIALS IN TISSUE ENGINEERING
17. Cell Interactions with Polymers
18. Polymer Scaffold Fabrication
19. Biodegradable Polymers
20. 3D Scaffolds
PART FIVE: TRANSPLANTATION OF ENGINEERED CELLS AND TISSUES
21. The Role of the Host Immune Response in Tissue Engineering and Regenerative Medicine
22. Tissue Engineering and Transplantation in the Fetus
23. in the Development of Immunoisolation Devices
PART SIX: STEM CELLS
24. Embryonic Stem Cells
25. Induced Pluripotent Stem Cells
26. Neonatal Stem Cells in Tissue Engineering
27. Embryonic Stem Cells as a Cell Source For Tissue Engineering
28. Postnatal Stem Cells in Tissue Engineering
PART SEVEN: GENE THERAPY
29. Gene Therapy
30. Gene Delivery into Cells and Tissues
PART EIGHT: BREAST
31. Breast Tissue Engineering: Reconstruction Implants and Three-Dimensional Tissue Test Systems
PART NINE: CARDIOVASCULAR SYSTEM
32. Progenitor Cells and Cardiac Homeostasis and Regeneration
33. Cardiac Tissue Engineering
34. Blood Vessels
35. Tissue-Engineering Heart Valves
PART TEN: ENDOCRINOLOGY AND METABOLISM
36. Generation of Pancreatic Islets from Stem Cells
37. Bioartificial Pancreas
38. Thymus and Parathyroid Organogenesis
PART ELEVEN: GASTROINTESTINAL SYSTEM
39. Stem Cells in the Gastrointestinal Tract
40. Liver Stem Cells
41. Hepatic Tissue Engineering
PART TWELVE: HEMATOPOIETIC SYSTEM
42. Hematopoietic Stem Cells
43. Blood Components from Pluripotent Stem Cells
44. Red Blood Cell Substitutes
45. Lymphoid Cells
PART THIRTEEN: KIDNEY AND GENITOURINARY SYSTEM
46. Stem Cells in Kidney Development and Regeneration
47. Tissue Engineering of the Kidney
48. Bladder and Urethra
49. Female Reproductive Organs
50. Male Reproductive Organs
PART FOURTEEN: MUSCULOSKELETAL SYSTEM
51. Mesenchymal Stem Cells in Musculoskeletal Tissue Engineering
52. Bone Regeneration
53. Tissue Engineering for Regeneration and Replacement of the Intervertebral Disc
54. Articular Cartilage Injury
55. Engineering Cartilage and Other Structural Tissues: Principles of Bone and Cartilage Reconstruction
56. Tendons and Ligament Tissue Engineering
57. Skeletal Tissue Engineering
PART FIFTEEN: NERVOUS SYSTE
58. Brain Implants
59. Brain-Machine Interfaces
60. Spinal Cord
61. Protection and Repair of Hearing
PART SIXTEEN: OPHTHALMIC
62. Stem Cells in the Eye
63. Corneal Replacement Tissue
64. Retinal Degeneration
65. Vision Enhancement Systems
PART SEVENTEEN: ORAL/DENTAL APPLICATIONS
66. Biological Tooth Replacement and Repair
67. Tissue Engineering in Oral and Maxillofacial Surgery
68. Periodontal Tissue Engineering
PART EIGHTEEN: RESPIRATORY SYSTEM
69. Tissue Engineering for the Respiratory Epithelium: Cell-Based Therapies for Treatment of Lung Disease
70. Lung Tissue Engineering
PART NINETEEN: SKIN
71. Cutaneous Epithelial Stem Cells
72. Wound Repair: Basic Biology to Tissue Engineering
73. Bioengineered Skin Constructs
PART TWENTY: TISSUE-ENGINEERED FOOD
74. Principles of Tissue Engineering for Food
75. Prospects for In Vitro Cultured Meat
PART TWENTYONE: EMERGING TECHNOLOGIES
76. 3D Bioprinting
77. Biofabricated 3D Tissue Models
78. Body-on-a-Chip
79. Monitoring and Real-Time Control of Tissue Engineered Systems
80. Bio-Manufacturing for Regenerative Medicine
PART TWENTYTWO: CLINICAL EXPERIENCE
81. Tissue-Engineered Skin Products
82. Tissue-Engineered Cartilage Products
83. Bone Tissue Engineering: Clinical Challenges and Emergent Advances in Orthopedic and Craniofacial Surgery
84. Tissue-Engineered Cardiovascular Products
85. Tissue-Engineered Organs
PART TWENTYTHREE: REGULATION, COMMERCIALIZATION AND ETHICS
86. The Regulatory Process from Concept to Market
87. Business Issues
88. Ethical Issues

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